(# Co-first author, * Co-corresponding author)
2024
Antitumor efficacy of a sequence-specific DNA-targeted γPNA-based c-Myc inhibitor, Cell Reports Medicine (2024)
Malik, S., Pradeep, S.P., Kumar, V., Xiao, Y., Deng, Y., Fan, R., Vasquez, J.C., Singh, V., and Bahal, R
2023
Microtechnologies for single-cell and spatial multi-omics, Nature Reviews Bioengineering (2023)
Deng, Y.#*, Bai, Z.#*, Fan R.*
Spatially resolved epigenome-transcriptome co-profiling of mammalian tissues at the cellular level, Nature (2023) (Highlight in Nature Reviews Genetics, Nature Methods)
Zhang, D.#, Deng, Y.#*, Kukanja P, Agirre E, Bartosovic M, Dong M, Ma C, Ma S, Su G, Bao S, Liu Y, Xiao Y, Rosoklija GB, Dwork AJ, Mann JJ, Leong KW, Boldrini M, Wang L, Haeussler M, Raphael BJ, Kluger Y, Castelo-Branco G*, Fan R.*
High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq, Nature Biotechnology (2023)
Liu, Y., DiStasio, M., Su, G., Asashima, H., Enninful, A., Qin, X., Deng, Y., Nam, J., Gao, F., Bordignon, P., Cassano, M., Tomayko, M., Xu, M., Halene, S., Craft, J., and Fan, R.
Anti-seed PNAs targeting multiple oncomiRs for brain tumor therapy, Science Advances (2023)
Wang, Y., Malik, S., Suh, H.W., Xiao, Y., Deng, Y., Fan, R., Huttner, A., Bindra, R.S., Singh, V., Saltzman, W.M. and Bahal, R.
2022
Spatial profiling of chromatin accessibility in mouse and human tissues, Nature (2022) (Highlight in Nature Structural & Molecular Biology)
Deng, Y., Bartosovic, M., Ma, S., Zhang, D., Kukanja, P., Xiao, Y., Su, G., Liu, Y., Qin, X., Rosoklija, B.R, Dwork, A., Mann, J.J., Xu, M.L., Halene, S., Craft, J.E., Leong, W.K., Boldrini, M., Castelo-Branco, G. and Fan, R.
Spatial-CUT&Tag: spatially resolved chromatin modification profiling at the cellular level, Science (2022)
Deng, Y., Bartosovic, M., Kukanja, P., Zhang, D., Liu, Y., Su, G., Enninful, A., Bai, Z., Castelo-Branco, G. and Fan, R.
In vivo correction of cystic fibrosis mediated by PNA nanoparticles, Science Advances (2022)
Piotrowski-Daspit, A.S., Barone, C., Lin, C.Y., Deng, Y., et al.
Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL, Science Advances (2022)
Bai, Z.#, Woodhouse, S.#, Kim, D., Lundh, S., Baysoy, A., Sun, H., Deng, Y., et al.
Cross-platform analysis reveals cellular and molecular landscape of glioblastoma invasion, Neuro-oncology (2022)
Chen, A., Xiao, Y., Tang, X., Baqri, M., Gao, X., Reschke, M., Zhou, Y., Deng, G., Zhang, S., Deng, Y., et al.
Single-Cell Transcriptomics Revealed Subtype-Specific Tumor-Immune Microenvironments in Human Glioblastomas, Frontiers in Immunology (2022)
Xiao, Y#, Wang, Z#, Zhao, M#, Deng, Y., et al.
CD44-Mediated Poor Prognosis in Glioma Is Associated With M2-Polarization of Tumor-Associated Macrophages and Immunosuppression, Frontiers in surgery (2022).
Xiao, Y.#, Yang, K.#, Wang, Z., Zhao, M., Deng, Y., et al.
2021
Spatial multi-omics sequencing for fixed tissue via DBiT-seq, STAR Protocols (2021)
Su, G., Qin, X., Enninful, A., Bai, Z., Deng, Y., Liu, Y. and Fan, R.
2020
High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue, Cell (2020) (Highlight in Nature Methods)
Liu, Y#, Yang, M#, Deng, Y#, Su, G, Enninful, A, Guo, C, Tebaldi, T, Zhang, D, Kim, D, Bai, Z, Norris, E, Pan, A, Li, J, Xiao, Y, Halene, S and Fan, R.
Ultra-Sub-Poisson Single-Cell RNA-Sequencing Enabled by an Active Trapping and Transfer Approach, ACS Nano (2020)
Bai, Z, Deng, Y, Kim, D, Chen, Z, Xiao, Y and Fan, R.
2019
Single-cell omics analyses enabled by microchip technologies, Annual Review of Biomedical Engineering (2019)
Deng, Y, Finck, A, and Fan, R.
Hydroporator: A hydrodynamic cell membrane perforator for high-throughput vector-free nanomaterial intracellular delivery and DNA origami biostability evaluation, Lab on a Chip (2019) (Featured as cover image)
Kizer, M#, Deng, Y#, Kang, G-Y, Paiyz, M, Wang, X and Chung, AJ
Microfluidics-enabled orientation and microstructure control of macroscopic graphene fibres, Nature Nanotechnology (2019)
Xin, G, Zhu, W, Deng, Y, Chung, AJ, De, S and Lian, J
2018
Intracellular delivery of nanomaterials via an inertial microfluidic cell hydroporator, Nano Letters (2018)
Deng, Y, Kizer, M, Rada, M, Sage, J, Wang, X, Cheon, DJ and Chung, AJ
DIY 3D Microparticle Generation from Next Generation Optofluidic Fabrication, Advanced Science (2018)
Paulsen, K, Deng, Y and Chung, AJ
2017
Inertial microfluidic cell stretcher (iMCS): Fully automated, high-throughput, and near real-time cell mechanotyping, Small (2017) (Featured as cover image)
Deng, Y, Davis, SP, Yang, F, Paulsen, KS, Kumar, M, Sinnott-DeVaux, R, Wang, X, Conklin, DS, Oberai, A, Herschkowitz, JI and Chung, AJ
2014
Development of a distributed-parameter model for the evaporation system in a supercritical W-shaped boiler, Applied Thermal Engineering (2014)
Zheng, S, Luo, Z, Deng, Y, Zhou, H
Analysis of the hydraulic resistance of a water wall based on a distributed parameter model in a supercritical once-through boiler, Journal of Thermal Science and Engineering Applications (2014)
Luo, Z, Deng, Y, Zheng, S, Zhou, H
2013
Magnetic separation of particles and cells in ferrofluid flow through a straight microchannel using two offset magnets, Journal of Magnetism and Magnetic Materials (2013)
Zeng, J, Deng, Y, Vedantam, P, Tzeng, TR, Xuan, X